Perspectives on Postmastectomy Radiation Therapy for Persistent Nodal Disease After Neoadjuvant Chemotherapy: Is Hindsight 20/20?
نویسندگان
چکیده
منابع مشابه
Role of postmastectomy radiation therapy after neoadjuvant chemotherapy in locally advanced breast cancer.
Neoadjuvant chemotherapy for primary breast cancer is the gold standard in the treatment of locally advanced, inoperable breast cancer, and also based on a large body of evidence has become a standard treatment option for patients with operable disease, who are clear candidates for adjuvant chemotherapy. There are several advantages of administering neoadjuvant chemotherapy: tumor downstaging, ...
متن کاملPostmastectomy Radiotherapy for Locally Advanced Breast Cancer Receiving Neoadjuvant Chemotherapy
Neoadjuvant chemotherapy (NAC) is widely used in locally advanced breast cancer (BC) treatment. The role of postmastectomy radiotherapy (PMRT) after NAC is strongly debated. The aim of our analysis was to identify major prognostic factors in a single-center series, with emphasis on PMRT. From 1997 to 2011, 170 patients were treated with NAC and mastectomy at our center; 98 cases (57.6%) underwe...
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A recently published review of the literature on postmastectomy radiation therapy (PMRT) for inflammatory breast cancer (IBC) cited a range for 5-year locoregional control (LRC) after PMRT from 73% to 92% (1). Even examining only contemporary datasets, these rates of LRC are lower than those reported for non-IBC (ie, 97% at 5 years [2]), and some authors have shown directly that IBC presentatio...
متن کاملConsensus Statement on postmastectomy radiation therapy.
1. Reduction in the recurrence rate of clinically detectable local-regional disease by PMRT is evident. 2. The most recent randomized controlled trials, including two well-designed trials using modern radiation techniques, have shown a moderate and statistically significant improvement in survival. 3. Consultation with a radiation oncologist should occur in postmastectomy node-positive patients...
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Déjà vu All Over Again? Although a substantial number of women will suffer and die from breast cancer during the upcoming years, we clearly have made stepwise progress in treating patients with this cancer over the last 3 decades. Each of these steps of progress has led to what are glibly designated “paradigm shifts.” Perhaps the most hotly debated of these paradigms is the local vs systemic na...
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ژورنال
عنوان ژورنال: International Journal of Radiation Oncology*Biology*Physics
سال: 2017
ISSN: 0360-3016
DOI: 10.1016/j.ijrobp.2017.07.020